The study, published this month in the journal Cell, bears importance because it’s the best explanation yet of resveratrol’s mechanisms for controlling pathways of energy regulation and mitochondrial health that scientists say are similarly affected by caloric restriction. This new understanding will likely provide the foundation for future resveratrol research.
In this study, researches questioned resveratrol’s action on the sirtuin enzyme family. Upon further tracing of cells’ metabolic activity, these researchers found that the main target for resveratrol’s health benefits is actually on proteins known as phosphodiesterases (PDEs) in skeletal muscle. By preventing the actions of PDEs, resveratrol initiates a cascade of events in the cell, including the indirect activation of sirtuins.
The researchers also found that, apart from its action on PDEs, resveratrol stimulated activity of a protein called glucagon-like peptide (GLP). GLP belongs to a class of molecules called incretins, which are involved in regulating secretion of insulin and improving glucose tolerance.
While researchers continue to pin down the exact health-promoting pathways of resveratrol, it doesn’t hurt to include it in your own health-promoting habits. Ageless Actives provides 250 milligrams of resveratrol in every serving, along with ample doses of vitamin D (1000 International Units) and coenzyme Q10 (100 milligrams). This three-in-one supplement is designed to support healthy aging from within based on the latest of exciting results in resveratrol and aging research.
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